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Multisystem Inflammatory Syndrome in Children

This document aims to ensure that clinicians are aware of current guidance regarding Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with Coronavirus Disease 2019 (COVID-19), including the case definition and guidance on reporting to local health departments.

Current Illinois MIS-C Data

Illinois has received 172 reports of MIS-C from clinicians with many other cases currently under investigation. The 172 cases have been submitted to the Centers for Disease Control and Prevention (CDC) for further reporting and review. The CDC has determined four reports are considered not to be a case. Additional cases being investigated will be counted and reported as soon as all necessary data are received and reviewed. Below is a graph depicting the reported cases by the onset month of their reported MIS-C illness. IDPH anticipates additional reports will be received as reporting for these cases can lag as the critical task of treating these patients becomes the clinicians’ priority.

Reported MIS-C Cases by Onset Month in Illinois, 2020-2021